Ankylosing Spondylitis Spondylothesis

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It remains the role of the radiologist to keep a look-out for early radiological abnormalities in susceptible patients.

Spondylolisthesis is a spinal condition that affects the lower vertebrae (spinal bones).

Risk factors are repetitive hyperextension of the spine (e.g., gymnastics), trauma, bone pathologies, or degenerative spine disease.

Spondylolisthesis may be asymptomatic or cause lumbar pain on exertion, gait problems, radiculopathic pain, or urinary incontinence. Surgical treatment (e.g, vertebral fusion, decompression of the nerves) is reserved for patients with refractory cases and neurologic deficits.

These spondylo-arthropathies can be divided into 5 major groups: () undifferentiated spondylo-arthropathy.1 AS is a debilitating disease, affecting mostly white men, with a male:female ratio of about 6:1 within the age group 15 - 35 years of age.

Early lumbar axial ankylosis and spinal involvement is more marked in male patients than female, with early radiographic signs of hip involvement.2-4 Classic joint involvement includes: bilateral sacro-iliac, thoraco-lumbar and lumbo-sacral joints (early) and cervical spine (late).5 The peripheral skeleton is involved in 10 - 20% of cases, with apical fibrosis of the lung parenchyma reported in only 1% of AS patients.6 Additional cardiac manifestations, such as aortic valve and root abnormalities, and with conduction and rhythm abnormalities, have also been reported in 2 - 10% of patients.6 Genetic susceptibility has been mentioned as a causative factor, with 96% of patients testing positive for the HLA-B27 gene.1 Associated diseases include: ulcerative colitis, iritis and aortic insufficiency.

Read the full story Living with AS is a bit like getting home to find there’s a gorilla in your house.

Ankylosing spondylitis is a debilitating disease that is one of the sero-negative spondylarthropathies, affecting more males than females in the proportion of about 6:1 in the age group 15 - 35 years of age.

Overall, children and adolescents achieve better results than adults and elderly.

Researchers at the University of Aberdeen are looking for people diagnosed with axial spondyloarthritis (axial Sp A) including ankylosing spondylitis (AS) to take part in a stakeholder consensus exercise.

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